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Publications:
1.FULL-LENGTH
PUBLICATIONS
1). Wang GW, Liem DA, Vondriska TM, Honda
HM, Korge P, Pantaleon DM, Qiao X, Wang YB, Weiss JN, Ping
P. Nitric oxide donor protect the murine myocardial against
infarction via modulation of mitochondrial permeability transition.
Am J Physiol. (Summitted).
2).
Wang GW*, Bolli R, Vondriska TM, Guo Y, Zhang
J, Prabhu SD, Zhang S, Tsai LL, Cardwell E, Zong NC, Korge
P, Bhatnagar A, Ping P. Acrolein exacerbates myocardial ischemic
injury by disrupting PKCe protective signal transduction.
Circulation (Summitted).
3). Vondriska TM, Ping PP, Zhang J, Lu M, Tang XL, Bolli R,
Wang GW*. Bmx, a member of the Tec family
of non-receptor tyrosine kinases, is a novel participant in
pharmacological cardioprotection. J Mol Cell Cardiol (Summited,
* Senior author)
4). Ping P, Baines CP, Gu Y, Prabhu SD, Zhang J, Tsai LL,
Cardwell E, Zong N, Vondriska TM, Korge P, Bhatnagar A, Wang
GW*. Cardiac toxic effects of trans-2-hexenal are
mediated by induction of cardiomyocyte apoptotic pathways.
Cardiovasc Toxicol. 3: 341-351, 2003 (* Senior author).
5).
Prabhu SD, Wang GW, Luo J, Gu Y, Ping P.
Chandrasekar B. Beta-adrenergic receptor blockade modulates
Bcl-X(s) expression and reduces apoptosis in failing myocardium.
J Mol Cell Cardiol. 35: 483-493, 2003.
6). Zhang J, Ping P, Vondriska TM, Tang XL, Wang GW,
Cardwell EM, Bolli R. Cardioprotection involves activation
of NF-kB via PKC-dependent tyrosine and serine phosphorylation
of IkB-a. Am J Physiol. 285: H1753-1758, 2003.
7). Wang GW, Song C, Vondriska TM, Klein
JB, Cao X, Zhang J, Kang YJ, D’Souza S, Ping P. Molecular
conformation dictates module formation: Example of PKCe and
Src tyrosine kinase. Am J Physiol. 282: H1166-1171, 2002.
8). Baines CP, Zhang J, Wang GW, Zheng YT,
Xiu YX, Cardwell EM, Ping P. PKCe and MAPK form signaling
modules in the murine heart: enhanced mitochondrial PKCe-MAPK
interactions and differential MAPK activation in PKCe-induced
cardioprotection. Circ Res. 90:390-397, 2002.
9). Wang JF, Yang Y, Wang GW, Min J, Sullivan
MF, Ping P, Xiao YF, Morgan JP. Embryonic stem cells attenuate
viral myocarditis in murine model. Cell Transplant 11: 753-758,
2002.
10). Klein JB, Wang GW, Zhou Z, Buridi A,
Kang YJ. Inhibition of tumor necrosis factor-a-dependent cardiomyocyte
apoptosis by metallothionein. Cardiovasc Toxicol. 2: 209-218,
2002.
11). Cai L, Li W, Wang GW, Kang YJ. Metallothionein
inhibits high glucose-induced apoptosis in cardiomyocytes.
Diabetes 51: 1938-1948, 2002.
12).
Wang GW, Klein JB, Kang YJ. Metallothionein
inhibits doxorubicin-induced mitochondrial cytochrome c release
and caspase-3 activation in cardiomyocytes. J Pharmacol Exp
Ther. 298: 461-468, 2001.
13). Wang GW, Zhou ZX, Klein JB, Kang YJ.
Inhibition of hypoxia/reoxygenation-induced apoptosis in metallothionein-overexpressing
cardiomyocytes. Am J Physiol. 280: H2292-2299, 2001.
14). Lembert JC, Wang GW, Kang YJ. Zinc inhibits
caspase-3 activation but not apoptosis induced by adriamycin.
Toxicol Appl Phamacol. 175: 89-93, 2001.
15). Kang YJ, Zhou ZX, Wang GW, Buridi A,
Klein JB. Suppression by metallothionein of doxorubicin-induced
cardiomyocyte apoptosis through inhibition of p38 mitogen-activated
protein kinases. J Biol Chem. 275:13690-13698, 2000.
16). Kang YJ, Zhou ZX, Wu HY, Wang GW, Saari
JT, Klein JB. Metallothionein inhibits myocardial apoptosis
in copper-deficient mice: Role of atria natriuretic peptide.
Lab Invest. 80:745-757, 2000.
17). Wang GW, Kang YJ. Inhibition of doxorubicin
toxicity in cultured neonatal mouse cardiomyocytes with elevated
metallothionein levels. J Pharmacol Exp Ther. 288: 938-944,
1999.
18). Wang GW, Schuschke DA, Kang YJ. Metallothionein
overexpressing neonatal mouse cardiomyocytes are resistant
to H2O2 toxicity. Am J Physiol. 276: H167-175, 1999.
19). Wang GW, Hu XQ, Wen FX. A comparative
study on the response to St. Thomas cardioplegic solution
in neonatal and adult isolated rabbit heart during ischemia
and reperfusion. Chinese Circulation J. 2:149-151, 1997.
20). Wang GW, Wang F. Protection of selenium
and vitamin E on cultured cardiac myocytes injured by lipid
peroxidation. Chinese J Endemiol. 15: 75-78, 1996.
21). Wang GW, Zhao YZ, Wang F, Zhao ZT. Protective
effect of vitamin E on lipid peroxidation in cultured heart
cells of neonatal rats. Acta Nutrimenta Sinica 18: 284-287,
1996.
22). Wang GW, Zhao YZ, Wang F, Li TY. Effect
of cumene hydroperoxide induced changes on vitamin E content
and membrane fluidity of cultured neonatal rat heart cells.
Acta Nutrimenta Sinica 18: 35-38, 1996.
23). Wang GW, Wang F, Wang LZ. Protective
effect of selenium on myocardial cells in culture to oxygen
and glucose deprivation. Chinese J Control Endemic Dis. 11:137-139,
1996.
24). Wang GW, Zhao YZ, Wang F. Protection
of selenium on cumene hydroperoxide-induced ultrastructure
injury in cultured cardiomyocytes. Studies of Trace Elements
and Health 13: 8-9, 1996.
25). Wang GW, Wang F, Zhao YZ, Wang LZ, Zhou
XB, Sun B, Zhang PY, Xi SG. Effect of cumene hydroperoxide
on DNA in cultured neonatal rat heart cells. J Norman Bethune
Univ Med Sci. 22: 226-228, 1996.
26).
Wang GW, Wang F, Li C. Effect of sodium nitrite
on cultured cardiac cells. Chinese J Endemiol 14: 345-347,
1995.
27). Wang GW, Zhao YZ, Wang F. Effect of
selenium on cumene hydroperoxide-induced DNA damage in cultured
cardiomyocytes. Studies of Trace Elements and Health 12:14-15,
1995.
28).
Wang GW, Wang F, Zhao YZ, Sun B. Protective
effect of selenium on cardiac cellular injury by lipid peroxidation
in culture. Studies of Trace Elements & Health 11: 17-19,
1994.
29).
Wang GW, Zhao YZ, Wang F, Li C, Chen Y. Injurious
effect of cumene hydroperoxide on cultured cardiac cells.
J Norman Bethune Univ Med Sci. 19: 441-443, 1993.
30).
Yang XD, Wang GW: Scanning electron microscopic
research on dental plaque in human palate mucous. J Norman
Bethune Univ Med Sci. 19: 269-270, 1993.
31).
Wang GW, Kang DR, Yang Q, Wang F. Changes of NADH-methemoglobin
reductase activity in erythrocytes of rats fed on grains from
Keshan Disease area and the influence of selenium and vitamin
E, B1. Chinese J Control Endemic Dis. 6: 193-195, 1991.
32). Wang F, Kang DR, Yang Q, Wang GW: Study
on pathogenesis for Keshan Disease. Chinese J Endemiol 8:
52-54, 1989.
2.BOOK
CHARPTERS
Wang
GW, Wu HY, Kang YJ. Metallothionein and its importance
to glutathione in cardiac protection against doxorubicin toxicity.
In Metallothionein IV, Ed. C.D. Klaassen, 517-522, Basel;
Boston; Berlin; Birkhauser; 1999.
3. PUBLISHED ABSTRACTS (Selected)
1).
Wang GW, Vondriska TM, Honda HM, Liem DA,
Qiao X, Korge P, Pantaleon DM, Wang Y, Weiss JN, Ping P. Nitric
oxide-induced late phase of preconditioning involves modulation
of mitochondrial permeability transition. FASEB J. Abstract.
2004.
2).
Wang GW, Bolli R, Vondriska TM, Guo Y, Zhang
J, Prabhu SD, Zhang S, Tsai LL, Cardwell EM, Zong NC, Korge
P, Weiss JN, Bhatnagar A, Ping P. Environmental acrolein exposure
impairs mitochondrial function and disrupts nitric oxide-induced
cardioprotection. Snowbird AHA Abstract. 2003.
3).
Vondriska T, Chen J, Wang GW, Lu M, Qiao
X, Zhang J, Pantaleon D, Honda H, Roos K, Ping P. The scaffolding
protein oracle is necessary mediator of nitric oxide-induced
cardioprotection. Circulation Suppl 108: IV-127, 2003.
4).
Shiraishi I, Melendez J, Younhkeun A, Vondriska T, Wang
GW, Welch S, Schaefer E, Schaefer E, Walsh K, Rosenzweig
A, Sussman M. Nuclear targeting of Akt enhances kinase activity
and survival of cardiomyocytes. Circulation Suppl 108: IV-115,
2003.
5).
Wang GW, Baines CP, Gu Y, Prabhu SD, Bhatnagar
A, Ping P. Chronic exposure induces myocardial dynsfunction,
myofibril disarray, and cardiomyocyte apoptosis in the mouse.
The FASEB J 16(Part I) A186, 2002.
6).
Wang GW, Baines CP, Gu Y, Guo Y, Zheng YT,
Bolli R, Prabhu SD, Ping PP. Chronic aldehyde exposure induces
cardiac injury and impairs nitric oxide-induced cardioprotection
in the mouse. Circulation Suppl II: 106: 280, 2002.
7).
Ping PP, Zhang J, Vondriska TM, Guo Y, Stidam JM, Cardwell
EM, Wang GW, Bolli R. Cardiac-specific transgenesis
of iNOS confers an infarct-sparing effects: Signaling mechanisms
invole site-specific iNOS tyrosine Phosphorylation by Src
Tyrosine kinase. Circulation Suppl II: 106: 278, 2002.
8).
Zhang J, Vondriska TM, Wang GW, Baines CP,
Stidam JM, Cardwell EM, Ping PP. Characterization of a signaling
complex by its protein composition, molecular architeture,
and spatial distribution: Defining the role of PKCe-Akt-eNOS
in cardioprotection via functional proteomics. Circulation
Suppl II: 106: 25, 2002.
9).
Wang GW, Zhang J, Baines CP, Song C, Zheng
Y, Klein JB, Kang YJ, Bolli R, Ping P. Cardioprotection involves
subcellular compartment-dependent localization of PKCe-Src
and PKCe-Lck signaling modules. J Mol Cell Cardiol. Suppl
II. 124, 2001.
10).
Baines CP, Wang GW, Zhang J, Zheng YT, Klein
JB, Kang YJ, Bolli R, Ping P. Mitochondrial co-localization
of MAPK with PKCe in the murine heart: increased mitochondrial
PKCe-MAPK signaling module formation in PKCe ??transgenic
mice. Circulation Suppl II. 102, 2001.
11). Zhang J, Bolli R, Zheng YT, Xiu JX, Wang GW,
Pierce WM, Ping P. Subcellular location is a major determinant
of PKCe complex assembly: a view gained via functional proteomic
analyses in cardioprotection. Circulation Suppl II. 209, 2001.
12). Zhang J, Wang GW, Baines CP, Zheng YT,
Ping P. Protein kinase Ce forms a signaling module with Akt
and eNOS: Differential modulation by myocardial protection
and myocardial toxicity. The FASEB J. 16(Part I) A177, 2002.
13).
Wang GW, Zhang J, Baines CP, Zheng Y, Klein
JB, Kang YJ, Bolli R, Ping P. Cardioprotection involves subcellular
compartment-dependent localization of PKCe-Src and PKCe-Lck
signaling modules. J Mol Cell Cardiol. Suppl II. 124, 2001.
14).
Baines CP, Wang GW, Zhang J, Zheng YT, Klein
JB, Kang YJ, Bolli R, Ping P. Mitochondrial co-localization
of MAPK with PKC? in the murine heart: increased mitochondrial
PKCe-MAPK signaling module formation in PKCe ??transgenic
mice. Circulation. Suppl II. 102, 2001.
15).
Zhang J, Bolli R, Zheng YT, Xiu JX, Wang GW,
Ping P. Subcellular location is a major determinant of PKCe
??complex assembly: a view gained via functional proteomic
analyses in cardioprotection. Circulation. Suppl II. 209,
2001.
16). Wang GW, Zhou ZX, Kang YJ. Effect of
metallothionein on doxorubicin-induced apoptosis in cardiomyocytes:
role of cytochrome c-activated caspase-3. The Toxicologist
114-114, 2000.
17). Lembert JC, Wang GW, Kang YJ. Supression
by zinc of doxorubicin-induced apoptosis: inhibition of caspase-3
activation. The Toxicologist 112-112, 2000.
18). Kang YJ, Wang GW, Zhou ZX, Klein JB.
Inhibition of metallothionein of oxidative stress-induced
apoptosis. The Toxicologist 411-411, 2000.
19). Klein JB, Wang GW, Zhou ZX, Buridi A,
Kang YJ. TNF-a stimulates cardiomyocyte apoptosis by a p38
MAPK-dependent pathway requiring reactive oxygen species.
The Toxicologis. 131-131, 2000.
20). Wang GW, Zhou ZX, Klein JB, Kang YJ.
Inhibition of apoptosis by hypoxia/reoxygenation in MT-overexpressing
cardiomyocytes. Free Radical Biol Med. 27: S117-S117, Suppl.
1; 1999.
21).
Klein JB, Wang GW, Zhou ZX, Buridi A, Kang
YJ. TNF stimulates cardiomyocyte apoptosis by a p38 MAPK pathway
that requires reactive oxygen species. Free Radical Bio Med.
27: S114-S114, Suppl. 1; 1999.
22).
Wang GW, Kang YJ. Inhibition by metallothionein
of doxorubicin toxicity in cultured mouse cardiomyocytes.
Free Radical Biol Med. 25: S41-S41, 1998.
23). Kang YJ, Wang GW. Metallothionein inhibits
doxorubicin-induced apoptosis in mouse heart. Free Radical
Biol Med. 25: S90-S90 Suppl. 1; 1998.
24).
Wang GW, Chen SG. Effect of sodium nitrite
on cell cycle in cultured neonatal rat heart cells. Mol Biol
Cell 7: 867-867 Suppl. S; 1996.
25).
Wang GW, Zhao YZ, Wang F, Chen Y. Injurious
effect of cumene hydroperoxide on cultured cardiac cells.
Chemical Abstracts 120: 211944v, 1994.
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