Ming Lu, M.D., Ph.D.
Postdoctoral Fellow

e-mail: jerryming2001@yahoo.com

Research interest:

PKC has been identified as one of the important factors that protect the heart against ischemic injury. The ability to alter specifically the expression or activity of PKC, as well as proteins that interact with PKC, in intact animals provides a powerful experimental approach to study pathophysiology. These animal models can be generated by transgenic technology. Recent works in this lab involve the exploration of the consequences of single and multiple gene mutations on complex physiological systems in vivo. Our research interest is to define the cardiac protective proteome by characterization of the cardiovascular phenotypes in genetically manipulated mice.

Publications:

1. Ming Lu, Kathy D. Miller, Yesim Polar, Harikrishna Nakshatri, Michael S. Kinch EphA2 overexpression in breast cancer decreases estrogen dependence. Submitted. 2002.

2. Ming Lu, James E. Klaunig, Lisa M. Kamendulis, Martha A. Belury. Dietary Conjugated Linoleic Acid Induces Apoptosis and Cell Proliferation in Liver of F344 Rats. Nutr Cancer. submitted. 2002.

3. Martha A. Belury, Silvia Y. Moya-Camarena, Ming Lu, Lingling Shi, Lisa A. Leesnitzer, Steven G. Blanchard. Conjugated Linoleic Acid is an Activator but not a High Affinity Ligand for Peroxisome Proliferator-Activated Receptor?amma. Nutrition Res 22: 817-824, 2002.

4. Ming Lu, Lingling Shi, Martha A. Belury. CLA Induction of Hepatic Gene Expression is Dependent on Phosphorylation of PPARalpha. In preparation.

5. Ming Lu, Martha A. Belury. 9Z11E-CLA Activation of PPARalpha: Implication for Hepatic Lipid Metabolism. In preparation.

6. Songbin Fu, Yu Li, Ming Lu, Pu Li. (1997) The Latest Molecular Biology and Biotechnology Laboratory Methods. Publisher: Heilongjiang Sci-tech Press.

7. Ming Lu, Peng Zhang. (1997) Cytogenetic Analysis of Human Primary Marrow Cells in Acute Leukemia. J. of Harbin Med. Univ., P. R. China.

8. Ming Lu, Shuxian Xing. (1996) Humoral Immunological Alternations in Chronic Hepatitis B Patients. J. of Harbin Med. Univ., P. R. China.

9. Ming Lu. (1994) Dynamic Analysis of Death Rate Due to Traffic Accidents in Zhaodong, Heilongjiang, P. R. China. (1994) J. of Harbin Med. Univ., P. R. China.